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VI. Potential Injuries Related To Anesthesia Or Anesthetic Procedures There is the possibility of injury related to anesthesia, and, especially, anesthetic procedures. Patients should also be informed about these, since the general public may not realize that these risks exist.
Peripheral Nerve Injury Proper positioning during surgery is extremely important to prevent peripheral nerve injury. Causes of such injury include prolonged position-related nerve compression or stretching, prolonged elbow flexion, prolonged lithotomy position placement (greater than four hours), prolonged tourniquet use (greater than two hours), or hereditary neuropathy with tendency to develop pressure palsies. If a patient has pre-existing neuropathy, the site should be noted before surgery. In addition, cigarette smoking and co-morbidities such as diabetes mellitus, alcoholism, cancer, and vitamin deficiency can predispose a patient to peripheral nerve injury. Because an anesthetized patient is unaware and unable to feel how he or she is positioned, it's up to operating room staff to position limbs appropriately. Any position that would not be tolerated by a fully awake patient should not be allowed for an anesthetized patient. The following chart lists interventions for the nerves most at risk for injury.
Tourniquet use for a blood-free surgical field is often needed for orthopedic procedures. The tourniquet is inflated to at least 50 mmHg above the patient's systolic blood pressure, and the application time and pressure are recorded on the anesthesia record. The tourniquet should not remain inflated for more than two hours at a time. The anesthesiologist alerts the surgeon at the end of each hour. If the tourniquet is needed after two hours, it's deflated for about 15 minutes. To avoid peripheral nerve injury, it's crucial that the tourniquet cuff be placed to avoid compressing a nerve against bone. In addition to nerve injury, skin injury can occur after prolonged or excessive pressure during surgery, which can result in ischemia and ulceration. Skin over bony prominences is especially vulnerable. Pressure from the anesthesia mask can cause ischemia on the bridge of the nose, the outer third of the eyebrows (which don't grow back if hair loss occurs), and the buccal branch of the facial nerve, causing paralysis of the orbicularis oris muscle (around the eye). The corner of the mouth can become ulcerated from endotracheal tube pressure, and the ear can be damaged if forcibly folded between the patient's head and operating table for a prolonged time. In surgeries where prolonged neck flexion occurs, severe postoperative macroglossia (enlarged tongue) has been noted, and care must also be taken that the patient's fingers and toes do not get pinched in a mechanically moving operating table. Finally, any orthopedic frames used to support the patient during orthopedic procedures should also be well padded to prevent nerve and skin ischemia.
Oral/Airway Injury Airway management is a crucial part of anesthesia delivery; there are a variety of tubes and techniques available to accomplish this. Tracheal intubation is common for patients undergoing general anesthesia, although mask or laryngeal mask airway (LMA) anesthesia maintenance can be used for short procedures not requiring muscle relaxants (outpatient or orthopedic procedures). To determine the appropriate equipment and technique, the patient's airway should be evaluated before surgery. The patient's upper airway is classified based on the size of the tongue and the pharyngeal structures visible on mouth opening, according to the following chart.
Class I Airway Oral and upper airway injury can occur during the intubation process, particularly if the patient has a difficult airway. The most common and serious type of damage is dental trauma; it's estimated that one in every 4,500 patients undergoing upper airway intubation during anesthesia experiences dental injury that requires further treatment (Stoelting & Miller, 2000). Part of the pre-surgical anesthesia evaluation includes noting the patient's current state of dentition and any areas of poor dentition that are especially likely to cause problems. The best way to avoid dental trauma is to avoid using the teeth as a lever for the laryngoscope while intubating. If a tooth is dislodged, it must be recovered, and appropriate radiographs should be taken of the chest to make sure the tooth hasn't passed into the trachea or distal airways. Oral and upper airway laceration and bruising can occur when physical force and/or multiple attempts are needed during a difficult intubation. Other complications after tracheal tube removal include laryngospasm, sore throat, laryngitis, laryngeal or subglottic edema, laryngeal ulceration, vocal cord paralysis, tracheitis, tracheal stenosis, and arytenoid cartilage dislocation.
Eye Injury
General anesthesia depresses airway reflexes, thus aspiration of gastric contents is another complication of tracheal intubation, especially in the period immediately after tube removal. This is most likely in debilitated patients, or if the patient ingested food soon before surgery (as may happen with trauma requiring surgery). Other predisposing conditions include bowel obstruction, pregnancy, morbid obesity, diabetic gastroparesis, symptomatic hiatal hernia, and gastroesophageal reflux. Aspiration can result in bronchospasm, atelectasis, hypoxemia, tachypnea, tachycardia, and hypotension, depending on the amount and pH of gastric contents aspirated. Patients at increased risk for aspiration may be pre-medicated before surgery, when possible, with antacids, H2-receptor antagonists (ranitidine), and/or metoclopramide.
Maternal/Fetal/Newborn Complications
Intraoperative Awareness
Awareness can occur in high-risk trauma and cardiac surgeries, or during Cesarean section, when a patient can't tolerate a deep anesthetic. In such cases, the anesthesiologist may decide that the risk of awareness is worth saving the patient's life. Alternatively, awareness can occur by user error, such as administering neuromuscular blocking agents without appropriate levels of hypnotic, or using an empty anesthetic canister (Bergman, Kluger, & Short, 2002). Brain-wave monitoring to detect the level of anesthesia during surgery can occasionally be useful. The BIS monitor (Bispectral Index) and the Patient State Analyzer (PSA) are examples of such monitors; the BIS is the most widely used. However, anesthesiology researchers say the value of brain-wave monitoring to prevent intraoperative awareness is uncertain, as there are reported cases of awareness despite BIS monitoring, thus the monitor appears to be less than 100% effective (O'Connor, Daves, Tung, Cook, Thisted, & Apfelbaum, 2001). It's cost prohibitive to use a brain-wave monitor on every surgical patient, and the ASA further states that "no monitoring device can replace the judgment of a physician…" (ASA, 2004). Although rare, intraoperative awareness can be life-changing for a patient who experiences it; some are left with posttraumatic stress disorder. Patients who have experienced intraoperative awareness should be supported and encouraged to seek counseling, when necessary. Patients who are afraid they may experience awareness in an upcoming surgery should be referred to the anesthesiologist for a complete discussion of the risks specific to the pending procedure. Research studies on the causes and solutions for intraoperative awareness are ongoing.
Allergic Reaction/Anaphylaxis
The ASA estimates that natural rubber latex is the cause of at least 10% of the anaphylactic reactions reported under anesthesia (http://www.asahq.org/publicationsAndServices/latexallergy.pdf). Approximately 1-6% of the general population and 8-12% of health care workers are sensitized to latex. Many medical supplies contain natural rubber latex, and sterile latex gloves are often used in surgery. Repeated exposure heightens sensitivity, so patients who have undergone multiple surgeries are one of the groups at highest risk for an anaphylactic reaction. It's imperative that latex precautions be used for latex-sensitive patients, and that they be scheduled as the first case of the day to avoid latex contamination from prior surgeries. Medications are another cause of allergic reaction, although it's important to distinguish between true allergic reaction and unpleasant side effects. Skin pruritus with hives or flushing, facial or oral swelling, shortness of breath, wheezing, choking, and vascular collapse are signs of allergic reaction. Antibiotics are the most common medication allergens, especially penicillin, sulfa, and cephalosporin derivatives. Seafood and shellfish allergies can signal the potential for cross-reaction to intravenous contrast dyes and protamine (a heparin-reversal agent), and allergy to soybean oil and egg yolk can signal a potential cross-reaction with propofol (an induction agent). History of an adverse effect to halothane or succinylcholine in a patient or close relative could signify malignant hyperthermia. Adverse reactions to anesthetic drugs include symptoms like nausea, vomiting, and pruritus. Unfortunately, many anesthetic medications cause unpleasant side effects. Patients should be encouraged to tell their anesthesiologist about any past unpleasant experiences so those problems can be anticipated and better controlled in future surgeries.
Case Study The orthopedic surgeon has seen Mrs. Parks and agrees that she needs a hip arthroplasty. As promised, you sit down with Mrs. Parks and her family to discuss her fears about the surgery, as well as what you learned at the Risks of Anesthesia inservice. She's most afraid of waking up during surgery, and asks you what the chances are of it happening again. Directions: 1. You respond that intraoperative awareness occurs:
2. Mrs. Parks' daughter says that she recently learned about BIS monitors in a nursing class. She wants to know how useful they are in preventing intraoperative awareness. You respond:
3. Mrs. Parks asks if she has to have general anesthesia for her hip surgery, or if there is another option. You respond:
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